Seminar PRIMO by Alveole: Engineering custom micro-environments
Date: Tuesday 11th June 2019
Time: 4pm
Location: Classroom 4, Hudson Beare building, Kings Buildings campus
Seminar: PRIMO Bioengineering platform by Alvéole
Presenter: Remi Pacaud, Business development Associate, Alvéole
Abstract:
In vitro, one of the challenges confronting cell biologists is to work with controlled and reproducible microenvironments to more efficiently study living cells and model diseases. PRIMO bioengineering technology gives cell biologists the flexibility to create and fine-tune in vitro cell microenvironments for more reliable and reproducible cell models. PRIMO utilises a contactless and maskless photopatterning module and a dedicated software (Leonardo). The platform can be used to structure cell culture substrates through photopolymerization and to functionalise any cell culture substrate surfaces (stiff or soft, flat or microstructured) through micropatterning. PRIMO can be used for a variety of applications in cell biology such as micropatterning, dynamic patterning, application of protein gradients on various substrates and 3D patterning in hydrogels. It is particularly suited for stem cell and primary cell experiments in order to generate 3D cell-based assays and predictive toxicology. With PRIMO, it is also possible to do microfabrication with photoresist materials (for example SU8), which can be used in microfluidic applications.
The PRIMO demo will be hosted by the Institute for Bioengineering and will be on loan for approximately 1 month. Training sessions will take place on Wednesday 12th and Thursday 13th of June. If you are interested in attending a training session or using the system while it is on loan, please contact Alison McDonald (dr.alison.mcdonald@ed.ac.uk).